About ENACT and taking part
What the research is, how an inquiry works, and what we do with your details.
Is this medical care?
No. This is research. Psilocybin is not FDA-approved for these conditions and is studied only in approved clinical trials.
Does sending an inquiry put me in a study?
No. Inquiries and intake calls are informational. Whether a study is a fit is decided later, in screening.
Screening follows a plan that an ethics review board has approved. That board is called an IRB.
Is there a cost?
Study procedures are at no cost to the people in a study. That is not the same as clinical care.
Who can take part in a study?
Each study sets out what it is looking for on its page under Research & Trials. Adults who match, after screening, can join. If a study has not opened yet, you can ask to hear when it does.
How do I start?
Fill out the intake form. We will arrange a short intake call — 15 to 30 minutes — about your interest and health history. It is a first look at whether a study is a fit, with no obligation.
If a study is not a fit for me, what then?
We will say so plainly. Research is not a substitute for care. If you are in immediate danger, call or text 988.
You can also search ClinicalTrials.gov (opens in a new tab) for other studies.
Will you diagnose me on the form?
No. A form on this site never diagnoses you and never turns you away. If you are in immediate danger, call or text 988.
Is taking part voluntary? Can I withdraw?
Yes. Taking part is voluntary. It begins with a consent form the study team goes through with you.
You can withdraw at any time without giving a reason.
Do I have to live in New Haven?
Visits are in person at Yale. We prefer people who can travel to 40 Temple Street. Taking part from outside the area is discussed case by case — the website does not decide.
Where is the lab?
ENACT is at 40 Temple St., 4th Floor, Suite 4C, New Haven, CT 06510, within Yale School of Medicine. Study visits are arranged with the study team.
Some multicenter trials also run at other sites. Each study page lists its sponsor and status.
Can my clinician refer me?
Yes. Referral does not commit you. We acknowledge the clinician within one business day.
I’m a clinician. How do I refer a patient?
Use the referral form. Tell us about yourself, the patient, and the study you have in mind.
Our team looks at whether the study is a fit and follows up with you. A referral does not commit your patient to taking part.
How do I stop you from contacting me?
Tell us which email or phone to drop and we stop writing and calling. You can also ask us to remove the contact details you gave. If you already joined a study, this does not take you out of it — call your study team for that.
Both take under a minute. No reason needed.
How is my information handled?
Contact details you share through our forms are transmitted securely and stored on Yale University’s HIPAA-compliant systems. Anything involving your health is discussed on the intake call rather than by form or email.
Does training certify me to practice?
No. Educational programs teach the science, ethics, and clinical context of this research. They do not certify independent psychedelic practice.
How can I support the research?
There are three ways, all on the Support page.
Fund a study: gifts are made securely through Yale University and directly support ENACT’s studies. Collaborate with us: research partnerships start with a conversation, so write to enact-research@enactresearch.com. Or stay updated through the lab’s occasional letter.
How do I hear about new results and new studies?
Subscribe to “A letter from the lab” on the Support page. It brings occasional updates on which studies are recruiting, what has published, and what comes next.
Studies in development
For the studies that are not open yet.
What does “in development” mean?
The protocol is being written. It has not finished ethics review and is not registered.
There is nothing to apply to. You may ask to be notified.
Can I sign up for one of these studies now?
These studies are in active protocol development. They are not open yet, and there is nothing to apply to. You can register early interest, and we will reach out the moment a study you might fit opens for screening.
Registering interest does not put you in a study and does not decide whether a study is a fit.
When will these studies open?
A research study moves through several stages before anyone can take part. These studies are at the earliest one.
Until a study clears ethics review and is registered, key details are not final. Those are who can join, what is involved, timing, and compensation. We do not publish them yet.
Is there a study I can join today?
While these are in development, other ENACT studies are actively recruiting.
Not seeing a study for you?
Our studies run in person in New Haven, and each one is looking for something specific. Other universities and hospitals run psychedelic research too.
ClinicalTrials.gov is the U.S. government’s public list of every registered study. You can search it by condition and by where you live.
Search ClinicalTrials.gov (opens in a new tab)We cannot search it for you, and we cannot refer you to another site.